Immune Dysregulation
POTS, MCAS & Autoimmunity
Chronic infections can trigger autonomic and immune dysfunction, manifesting as POTS, MCAS, and autoimmune conditions. Targeted molecular therapies address the underlying infectious drivers.
Clinical Insight
Postural Orthostatic Tachycardia Syndrome (POTS) and Mast Cell Activation Syndrome (MCAS) frequently co-occur with stealth infections. Addressing the microbial trigger can restore autonomic and immune balance.
Rule Out Infection First
Has infection actually been ruled out?
If you've been told you have an autoimmune condition, it's worth asking one question first: has infection actually been ruled out? Many autoimmune presentations are driven by underlying coinfections — often tick-borne — that standard Western blot and PCR testing simply aren't sensitive enough to catch. These are the same tests most doctors' offices rely on for a Lyme or coinfection workup, which is part of why so many of these infections go undiagnosed.
At Newport Integrative, we use next-generation sequencing and comprehensive tick-borne panels to look more thoroughly before you commit to an autoimmune diagnosis and its treatment path. If infection is present, treating it — rather than only managing symptoms — can change the course of your care.
Condition Profile
The infectious roots of dysautonomia & autoimmunity
POTS, MCAS & Autoimmunity
Autonomic and immune dysfunction triggered by chronic infection
Persistent pathogens can dysregulate the autonomic nervous system and destabilize mast cells, leading to orthostatic intolerance, histamine-driven inflammation, and autoimmune cascades. Oligonucleotide therapy targets the molecular drivers underlying these interconnected conditions.
Gene Targets
FAQ
POTS, MCAS & Autoimmunity — Frequently Asked Questions
Next Step
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